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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VDR
All Species:
25.15
Human Site:
S405
Identified Species:
61.48
UniProt:
P11473
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11473
NP_000367.1
427
48289
S405
S
K
Q
Y
R
C
L
S
F
Q
P
E
C
S
M
Chimpanzee
Pan troglodytes
A2T7D9
348
39540
G327
R
S
I
N
E
A
Y
G
Y
Q
I
Q
H
I
Q
Rhesus Macaque
Macaca mulatta
Q8SQ01
434
49974
L412
A
Q
H
T
Q
R
L
L
R
I
Q
D
I
H
P
Dog
Lupus familis
XP_543714
448
49978
S426
S
K
Q
Y
R
C
L
S
F
Q
P
E
C
S
M
Cat
Felis silvestris
Mouse
Mus musculus
P48281
422
47833
S400
S
K
Q
Y
R
S
L
S
F
Q
P
E
N
S
M
Rat
Rattus norvegicus
P13053
423
47795
S401
S
K
Q
Y
R
S
L
S
F
Q
P
E
N
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O42392
451
51281
S429
S
K
Q
Y
R
C
L
S
F
Q
P
E
H
S
M
Frog
Xenopus laevis
O13124
422
48170
S400
S
K
Q
Y
R
S
I
S
F
L
P
E
H
S
M
Zebra Danio
Brachydanio rerio
Q9PTN2
453
50848
S431
S
K
Q
Y
R
S
L
S
F
Q
P
E
H
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123279
490
55735
S460
M
K
L
T
E
L
R
S
L
N
N
S
H
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
39.8
88.3
N.A.
88.5
89.6
N.A.
N.A.
76
73.3
67.9
N.A.
N.A.
N.A.
N.A.
30.2
Protein Similarity:
100
51.9
56.2
91.7
N.A.
93.2
93.4
N.A.
N.A.
84.4
85
78.8
N.A.
N.A.
N.A.
N.A.
48.7
P-Site Identity:
100
6.6
6.6
100
N.A.
86.6
86.6
N.A.
N.A.
93.3
73.3
86.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
20
33.3
100
N.A.
86.6
86.6
N.A.
N.A.
93.3
80
86.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
30
0
0
0
0
0
0
20
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
20
0
0
0
0
0
0
70
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
50
10
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
10
10
0
10
10
0
% I
% Lys:
0
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
10
70
10
10
10
0
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% M
% Asn:
0
0
0
10
0
0
0
0
0
10
10
0
20
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
70
0
0
0
10
% P
% Gln:
0
10
70
0
10
0
0
0
0
70
10
10
0
0
10
% Q
% Arg:
10
0
0
0
70
10
10
0
10
0
0
0
0
0
0
% R
% Ser:
70
10
0
0
0
40
0
80
0
0
0
10
0
80
0
% S
% Thr:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
70
0
0
10
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _